Cell Processing Isolator (CPI)
The Cell Processing Isolator (CPI) is an integrated system that combines several types of equipment into one isolation technology.
It is designed to isolate the process to ensure operator safety without compromising product quality. It also provides a sterile ISO Class 5/Grade A environment that is required to carry out aseptic processes.
Applications:
● Allogenic Cell Therapy
● Autologous Cell Therapy
● Biosafety/Animal Biosafety Level 3/4 Containment
● Cell Banking
● Monoclonal Antibody Productiong
● Phase III Clinical Trial
● Protein Production
● Vaccine Research
● Virus Production
Features
● Modular and adaptable
● Pressure leak-tested
● Pass-through chamber
● Integrated BioVap™ biodecontamination system
● Cell therapy equipment integration
Principle
The CPI is highly modular and adaptable to meet the client’s requirements. General bioprocessing equipment such as a CO2 incubator and a centrifuge can be integrated into the isolator. These said, bioprocessing equipment are also manufactured by Esco.
Models
With Esco’s wide range of isolators, clients can easily choose their base isolator depending on their process requirements.
Additional options include integration of Esco cell therapy equipment, but also as a stand-alone isolator with third-party devices.
For clients requiring temperature and CO2 control, Turbulent Flow Aseptic Isolator (TFAI™) or Aseptic Containment Isolator (ACTI) can be used.
The advantage of TFAI over ACTI is the optional Pod Flange which allows integration of other equipment on the base and in the rear portion of the isolator.
For those needing cell therapy equipment integration on the base of the unit only, General Processing Platform Isolator (GPPI) and Advanced Processing Platform Isolator (APPI) are available.
While for those requiring a stand-alone unit (with own control system) connected to the isolator through electrical sockets, Esco offers the Streamline® Compounding Isolator (SCI) and the Isoclean® Healthcare Platform Isolator (HPI-G3).